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Russian military forces have destroyed a new laboratory at the Chernobyl nuclear power plant that among other things works to improve management of radioactive waste, the Ukrainian state agency responsible for the Chernobyl exclusion zone said Tuesday, Associated Press reported.

The Russian military seized the decommissioned plant at the beginning of the war. The exclusion zone is the contaminated area around the plant, site of the world’s worst nuclear meltdown in 1986.

The state agency said the laboratory, built at a cost of 6 million euros with support from the European Commission, opened in 2015.

The laboratory contained “highly active samples and samples of radionuclides that are now in the hands of the enemy, which we hope will harm itself and not the civilized world,” the agency said in its statement.

Radionuclides are unstable atoms of chemical elements that release radiation, according to the Associated Press.

In another worrying development, Ukraine’s nuclear regulatory agency said Monday that radiation monitors around the plant had stopped working.

Russia’s false accusation that Ukraine has biological and chemical weapons is a “clear sign” that a desperate Vladimir Putin is considering using them himself, Joe Biden has said, The Guardian reported.

The US president said Putin’s “back is against the wall and now he’s talking about new false flags he’s setting up including, asserting that we in America have biological as well as chemical weapons in Europe – simply not true. I guarantee you,” Biden said at an event on Monday.

“They are also suggesting that Ukrainehas biological and chemical weapons in Ukraine. That’s a clear sign he’s considering using both of those.

He’s already used chemical weapons in the past, and we should be careful of what’s about to come.”

Putin “knows there’ll be severe consequences because of the united Nato front,” he said, without specifying what actions the alliance would take, according to The Guardian.

The remarks echo previous comments by officials in Washington and allied countries, who have accused Russia of spreading an unproven claim that Ukraine had a biological weapons program as a possible prelude to potentially launching its own biological or chemical attacks.

Biden spoke after the Pentagon said it had seen “clear evidence” Russian forces were committing war crimes and that it was helping collect evidence. Last week, the US president said he thought Putin was a “war criminal”, as well as a “murderous dictator” and “thug”, comments the Russian foreign ministry said were “unworthy of a state figure of such a high rank” and risked rupturing US-Russian ties.

The UN’s international court of justice has already ordered Moscow to halt its invasion, and a prosecutor at the international criminal court has launched a war crimes investigation, The Guardian reported.

On Monday night, Ukrainian president Volodymyr Zelenskiy again urged direct talks with Putin, saying: “Without this meeting it is impossible to fully understand what they are ready for in order to stop the war.”

He also said his country will never bow to ultimatums from Russia and cities directly under attack, including the capital, Kyiv, and Mariupol and Kharkiv would not accept Russian occupation, according to The Guardian.

Ukrainian forces battled continuing Russian efforts to occupy Mariupol and claimed to have retaken a strategic suburb of Kyiv on Tuesday, mounting a defense so dogged that it is stoking fears Russia’s Vladimir Putin will escalate the war to new heights, Associated Press reported.

“Putin’s back is against the wall,” said US President Joe Biden, who is heading to Europe this week to meet with allies. “And the more his back is against the wall, the greater the severity of the tactics he may employ.”

Biden reiterated accusations that Putin is considering resorting to using chemical or biological weapons, though Pentagon spokesman John Kirby said the US has seen no evidence to suggest that such an escalation is imminent.

The warnings came as attacks continued in and around Kyiv and Mariupol, and people escaped the battered and besieged port city. Ukrainian President Volodymyr Zelenskyy accused Russian forces of not only blocking a humanitarian convoy trying to take desperately needed aid to Mariupol but seizing what another Ukrainian official said were 15 of the bus drivers and rescue workers on the aid mission, along with their vehicles.

Zelenskyy said the Russians had agreed to the route ahead of time, according to the Associated Press.

“We are trying to organize stable humanitarian corridors for Mariupol residents, but almost all of our attempts, unfortunately, are foiled by the Russian occupiers, by shelling or deliberate terror,” he said in his nightly video address to the nation.

The hands of one exhausted Mariupol survivor were shaking as she arrived by train in the western city of Lviv.

“There’s no connection with the world. We couldn’t ask for help,” said Julia Krytska, who was helped by volunteers to make it out with her husband and son. “People don’t even have water there.” 

Explosions and bursts of gunfire shook Kyiv, and heavy artillery fire could be heard from the northwest, where Russia has sought to encircle and capture several of the capital’s suburban areas.

Early Tuesday, Ukrainian troops drove Russian forces from the Kyiv suburb of Makariv after a fierce battle, Ukraine’s Defense Ministry said. The regained territory allowed Ukrainian forces to retake control of a key highway and block Russian troops from surrounding Kyiv from the northwest.

A video posted by Ukrainian police showed them surveying damage in Makariv, including to the town’s police station, which an officer says took a direct hit to its roof. The police drove by destroyed residential buildings and along a road pocked by shelling. The town appeared all but deserted, Associated Press reported.

Still, the Defense Ministry said Russian forces partially took other northwest suburbs, Bucha, Hostomel and Irpin, some of which have been under attack almost since Russia invaded nearly a month ago.

A Western official, speaking on condition of anonymity to discuss military assessments, said Ukrainian resistance has brought much of Russia’s advance to a halt but has not sent Moscow’s forces into retreat.

“We have seen indications that the Ukrainians are going a bit more on the offensive now,” Kirby told reporters separately in Washington. He said that was particularly true in southern Ukraine, including near Kherson, where “they have tried to regain territory.”

Asked on CNN what Russian President Vladimir Putin had achieved in Ukraine, Kremlin spokesman Dmitry Peskov said: “Well, first of all, not yet. He hasn’t achieved yet.” But he insisted that the military operation was going “strictly in accordance with the plans and purposes that were established beforehand.”

Putin’s aims remain to “get rid of the military potential of Ukraine” and to “ensure that Ukraine changes from an anti-Russian center to a neutral country,” Peskov said.

Russia’s far stronger, bigger military has many Western military experts warning against overconfidence in Ukraine’s long-term odds. Russia’s practice in past wars in Chechnya and Syria was to grind down resistance with strikes that flattened cities, killed countless civilians and sent millions fleeing, according to the Associated Press.

But Russian forces appeared unprepared and have often performed badly against Ukrainian resistance. The U.S. estimates Russia has lost a bit more than 10 percent of the overall combat capability it had at the start of the fight, including troops and tanks and other materiel.

The Supreme Court has issued an interim order not to immediately implement the election code of conduct’s requirement for people’s representatives to resign before filing nominations for the local elections.

Responding to a writ petition filed by Helambu Rural Municipality Chairman Nima Gyalzen Sherpa, a single bench of Justice Bam Kumar Shrestha on Tuesday ordered not to implement such provision till March 27.

Both the petitioner and defendant have been called on that day for discussion.