The White House has fired CDC Director Susan Monarez after she refused to resign, saying she was “not aligned with the president’s agenda.” Monarez’s lawyers accused Health Secretary Robert F. Kennedy Jr. of pressuring her to back “unscientific” policies, according to BBC.

Her removal sparked a wave of resignations, including the agency’s chief medical officer and leaders of infectious disease and immunisation programs, who cited misinformation and political interference.

The shake-up comes as the FDA restricted new Covid vaccines to seniors and high-risk groups, and amid widespread layoffs at the CDC, BBC reported.