A hat-trick by Paris St Germain midfielder Vitinha consigned Tottenham to another defeat, but Thomas Frank's team produced a battling display in defeat, Reuters reported.
Spurs were desperate for a response after Sunday's 4-1 thrashing at Arsenal and twice took the lead in the French capital through Richarlison and Randal Kolo Muani.
PSG loanee Kolo Muani grabbed his second against his parent club with 18 minutes left, but Vitinha sealed his treble soon after to end Tottenham's unbeaten run in the Champions League and leave them 15th in the league phase after five fixtures, according to Reuters.