Covid new variant: Not much to worry

India saw a single day rise of 656 new cases of coronavirus on Dec 24, pushing the active cases to 3,742 according to the Union Health Ministry. Amid the surge in cases of Covid-19, health experts have asked people to remain calm and follow Covid-appropriate behavior.

In Nepal, health experts have suggested people not to worry about the latest surge of coronavirus infection in India. They say that the mutations of the virus are always evolving, and this is one of the mutations of the omicron variant. 

“Though this strain is circulating faster, it is not very serious. It is not that scary. If you are vaccinated once or twice, or were previously infected there won’t be much severity if you get infected,” said Sameer Mani Acharya Dixit, chairperson and head of research at Intrepid Nepal Pvt Ltd.

The symptoms of the infection are similar to the infection caused by similar other variants of the coronavirus, such as headache, sore throat, fever, etc. Health experts, however, have advised people to take booster shots to prevent oneself from the severity of the infection.

What is JN.1?

JN.1 is a closely-related descendant of BA.2.86, a highly mutated strain that first worried scientists over the summer. BA.2.86 was deemed a “variant of interest” by the World Health Organization back in August.

The UN health body has recently designated JN.1 as a variant of interest, differentiating it from its parent lineage BA.2.86. The WHO defines variants of interest as strains that are worrying enough to trigger stepped up investigations of the variant by countries, like laboratory studies and field investigations of its outbreaks.

Despite its swift dissemination, the WHO has underscored that the overall risk associated with JN.1 is currently considered low based on available evidence.

In recent weeks, JN.1 was reported in multiple countries, and its prevalence has been rapidly increasing globally. But the WHO has maintained that there is no evidence to suggest any additional public health risk posed by the variant.

Concerns triggered

After first being spotted in the United States in September, the variant has spread across 41 countries.

Health experts say the JN.1 is spreading fast in all regions, probably because it has an additional mutation in the spike protein compared to the BA.2.86 variant from which it’s descended.

The outbreak of the JN.1 sub-variant of the coronavirus in India has triggered concerns among the Nepalis. Indian states Kerala, Karnataka, Tamil Nadu, Maharashtra, Goa, Puducherry, Gujarat, Telangana, Punjab and Delhi have reported a slight increase in the number of cases of late. 

According to the Indian media reports nearly 93 percent of those infected have mild symptoms and are isolating at home. Among those who are undergoing treatment at hospitals across the country, only 0.1 percent are on ventilator support, 1.2 percent are admitted into the intensive care unit and 0.6 are on oxygen support.

No need to panic

Nepal currently hasn’t seen a rise in the number of coronavirus cases. The authorities however say that they are closely monitoring the development in India.

“Many people in Nepal have had the infection and people have received at least two doses of the vaccine. Therefore, the probability of severe infection is low,” said Dr Prakash Budhathoki, spokesperson at the Ministry of Health and Population. “Intensive care units, oxygen plants, and other physical infrastructure constructed during the Covid-19 pandemic can be utilized if needed.” 

Following the surge in coronavirus cases, health desks established at checkpoints and international airports have been placed on standby, and a request has been made to place patients with respiratory problems under special supervision.

“As the infection is seen in Kerala, we are relatively at lower risks. If the infection was seen in the southern areas of India that borders Nepal, it would have been quite risky, as there are high chances for the variant to enter the country in a shorter time span,” said Dr Budhathoki. 

He also informed that patients with long-standing respiratory problems have been recommended for gene sequencing. The ministry has also requested health centers to keep a check on the people visiting the hospitals with the symptoms of coronavirus and has asked them to submit a report to the ministry.

“It is anticipated that this variant may cause an increase in Sars-Cov-2 [coronavirus] cases amid a surge of infections of other viral and bacterial infections, especially in countries entering the winter season,” the WHO said in its risk assessment.

The UN health agency also noted that there is still limited evidence on how capable JN.1 is of getting round the immunity offered by vaccines.

Strengthen surveillance

The WHO has urged countries in the South-East Asia region to strengthen surveillance and for people to take protective measures in view of increasing numbers of cases of respiratory diseases, including due to coronavirus and its new sub-variant JN.1, and influenza. 

“The Covid-19 virus continues to evolve, change and circulate in all countries globally. While current evidence suggests the additional public health risk posed by JN.1 is low, we must continue to track the evolution of these viruses to tailor our response. For this, countries must strengthen surveillance and sequencing, and ensure sharing of data,” said Dr Poonam Khetrapal Singh, WHO regional director for South-East Asia. 

Considering the available, yet limited evidence, the additional public health risk posed by JN.1 is currently evaluated as low at the global level. It is anticipated that this variant may cause an increase in Covid-19 cases amid a surge in infections of other viral and bacterial infections, especially in countries entering the winter season.

 Ways to protect

 Health experts have advised people to take protective measures and seek timely clinical care when unwell. They have also urged people with high risk such as elderly citizens, people with comorbid health conditions to take vaccination against coronavirus and influenza.

“All WHO-approved Covid-19 vaccines continue to protect against severe disease and death from all variants, including JN.1,” said Dr Singh. “With Covid-19 continuing to circulate at high levels globally, countries must strengthen surveillance, sequencing and reporting to effectively manage respiratory diseases and to protect people’s health.”

To prevent infections and severe disease, the WHO advises to:

• Wear a mask in crowded, enclosed areas
• Cover up coughs and sneezes
• Clean your hands regularly
• Stay up to date with covid and flu vaccinations, especially if vulnerable
• Stay home if ill
• Get tested if you have symptoms