Understanding PCOS: A growing health concern beyond fertility
Many people may have heard the term PCOS, which stands for Polycystic Ovary Syndrome, although its exact cause is still not fully understood. Today, PCOS is recognized as the most common hormonal and metabolic disorder affecting women of reproductive age, impacting 6-20 percent of women worldwide. PCOS is mainly characterized by high levels of male hormone (androgens) in women, irregular or absent ovulation, and the presence of multiple small cysts in the ovaries, which can be detected through ultrasound.
Originally described in 1935 as Stein-Leventhal Syndrome, PCOS was once viewed only as a reproductive problem, causing missed periods, irregular menstruation, and difficulty in becoming pregnant. However, decades of research have revealed that PCOS affects far more than fertility. It is now known to be a serious whole-body condition, closely linked to weight gain, abdominal obesity, high blood pressure, abnormal cholesterol levels, insulin resistance, and chronic low-grade inflammation—all of which significantly increase the risk of diabetes and heart disease.
The most widely used diagnostic method for PCOS is the Rotterdam criteria, which requires the presence of at least two of the following: excess male hormones, irregular ovulation, and polycystic ovaries.
In Nepal, limited studies indicate that about 5-7 percent of women aged 20-30 are diagnosed with PCOS during medical checkups, while data on other age groups remain scarce. Unfortunately, public awareness of the condition is still very low, and access to reliable diagnostic services is limited. As a result, many women are diagnosed only when they seek medical help for infertility. Once pregnancy is achieved, follow-up care often ends, even though the health risks associated with PCOS continue throughout a woman’s life.
What is most concerning is that long-term exposure to high androgen levels in women with PCOS can lead to serious metabolic health problems over time. Emerging research also suggests that these effects may even influence the health of children born to mothers with PCOS, highlighting the need for further studies.
PCOS is therefore not just a fertility issue; it is a lifelong health condition that requires early diagnosis, continuous care, and greater public awareness to protect the long-term health of women and future generations.
